Adding the compound solution included hydrochloric acid and hydrofluoric acid into coal seam, the pore structure of coal can be destroyed by acidizing treatment, and the permeability of coal seam can be improved. In order to increase the acidification damage effect, in this paper, the effects of anion surfactant named Sodium Dodecyl Sulfate (SDS) on the pressure relief and enlarge permeability effect of compound solution acidified coal were studied from four aspects: mechanical characteristics, porosity and pore distribution of coal samples, retention effect of fracturing fluid and microscopic morphology of coal sample surface. The results show that the SDS promotes the pressure relief effect of acidified coal body and reduces the strength of the treated coal sample. At the same time, the SDS increases the reaction area of acid fracturing fluid and impurity minerals in the fractures of coal sample, enhancing the acidification effect of HCL and HF on coal sample and increasing the porosity of coal. In the aspect of pore distribution, through the acidification synergism of SDS, the macropores and fractures of coal samples increase obviously. With the addition of SDS, the reversible work required for HCL and HF compound solution to break away from coal molecules is reduced by 18.45 J, which can significantly reduce the water blocking effect caused by the fracturing fluid retention, and improve the efficiency of coalbed methane extraction. After the compound solution erodes the coal sample, the microscopic morphology of coal sample surface has changed greatly, and the destruction degree of acidizing erosion is the highest after SDS synergism. The results of this paper are great significance for studying the mechanism of pressure relief and enlarge permeability effect of acidified coal. (C) 2019 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.