The hydroformylation of 1-dodecene was performed in microemulsion systems using rhodium sulfoxantphos as a catalyst. Preliminary experiments proved these aqueous multiphase systems to enable the reaction with good yield and very high selectivity toward the linear aldehyde (about 60% yield with n:iso ratio of 98:2 after 24 h reaction time). Catalyst recycling is easily possible by simple phase separation after the reaction, maintaining the activity and very high selectivity. The investigation of process parameters showed a first-order dependence of the initial rate with respect to the 1-dodecene concentration, and a more complex behavior with respect to catalyst concentration and syngas pressure. On the basis of an earlier proposed mechanism and the gained experimental data, an adapted kinetic model has been derived, including the unique influences of the regarded multiphase system on the reaction (in particular the surfactant concentration and ligand to metal ratio). The identified model formulation and parameter set for the reaction system enabled the calculation of reaction trajectories that are in good accordance to the observed trends from experimental data.