Nonuniform solid electrolyte interphase (SEI) layer leads to the dendrite growth, hindering the commercial application of lithium metal anode. Herein, we report a novel strategy to acquire a uniform and stable SEI layer by fragmenting solid electrolyte interphase using vertically aligned nanochannels of anodized aluminum oxide (AAO). As a result, AAO electrode with a pore radius of 400 nm renders the best cycle performances. Especially, this electrode can run stably for > 300 cycles at 1 mA/cm(2), with a high Coulombic efficiency of 97.2% and low polarization voltage of 39.5 mV, which is superior to the cycle performance of stainless steel (SS) and other AAO electrodes. Moreover, this electrode still can achieve a stable cycle at the high current density of 10 mA/cm(2) or high area capacity of 10 mAh/cm(2). Therefore, this strategy of fragmenting solid electrolyte interphase by vertically aligned nanochannels may open new doors for lithium metal anode.