The sandwich-structured MnTMPyP/NbWO6 nanocomposites were synthesized by the electrostatic self-assembly of the manganese porphyrin (MnTMPyP) cations with the exfoliated niobium tungstate [NbWO6](-) nanosheets. Various analytical techniques such as X-ray diffraction patterns, scanning electron micrograph, transmission electron microscope, energy-dispersive spectroscopy, UV-Vis absorption spectra and Fourier transform infrared spectra were used to determine the structure, composition and morphology of the as-prepared samples. It can be concluded that MnTMPyP cations were inserted into interlayer spacing of the [NbWO6](-) nanosheets and arranged in an inclined single layer at 58 degrees. The MnTMPyP/NbWO6 nanocomposites modified electrode exhibited excellent electro-catalytic oxidation activity toward nitrite in 0.2molL(-1) and pH 7.0 phosphate buffer solution. Additionally, the oxidation peak current is proportional to the square root of scan rates, indicating that the redox reaction of nitrite is a typical diffusion-controlled process. Also, the sensitivity and detection limit for nitrite at the modified electrode was evaluated as 3.80x10(-5)molL(-1) over a concentration range from 1.20x10(-4) to 3.57x10(-3)molL(-1) by using differential pulse voltammetry.