Spiro-OMeTAD, which took place of PEDOT:PSS as hole transport material, was used to assist P3HT to transport holes. Inverted hybrid solar cells using P3HT and spiro-OMeTAD with layered (Device A) and/or blended (Device B) structures were fabricated. Power conversion efficiency of 1.24% was achieved for the latter device vs 0.53% for the former one. Here, the blended surface was smoother for closer electrical contact with the Cu electrode, leading to more efficient collection of holes. This study is the first report on layered and blended structures of ZnO-based inverted hybrid solar cells with P3HT and spiro-OMeTAD.