The objective of this work is to introduce a nanocomposite based bioanode for biofuel cell application. The asprepared Kraton/MWCNTs nanocomposite was used as a current enhancer and ferritin (Frt) as a mediator between glucose oxidase (GOx) and the electrode surface. The hybrid anode achieved enzymatic oxidation of glucose by the nanocomposite reflecting an efficient energy conversion from glucose. The resulting Kraton/MWCNTs/Frt/GOx bioande exhibited good catalytic activity towards glucose oxidation along with excellent stability. The maximum current density attained by the bioanode is 1.14 mA cm(-2) at the optimum glucose concentration of 60 mM. This enzymatic strategy can be employed to develop other polysaccharide or oligosaccharide fuel cells in which glucose oxidation is involved.