Cooling rate in Run Out Table (ROT) in steel industries tailors microstructure which lead to improved mechanical properties. The current work aims to increase cooling performance of steel using TiO2 nanofluid as coolant in jet impingement. Different concentrations of TiO2 nanofluid have been used to study effect on jet cooling of a steel plate from 900 degrees C. Thermal conductivity of nanofluid is found to significantly enhance at optimum concentration and this plays major role in increasing cooling rate of the steel plate. 19% enhancement in cooling rate is observed by using 40 ppm of TiO2 nanofluid compared to water.