Pool boiling heat transfer performance of hydro-fluorocarbon refrigerant R-134a on titanium dioxide (TiO2) nanoparticle coated surface is experimentally studied in the article. The test surfaces, viz, 100 nm, 200 nm and 300 nm thick TiO2 nanoparticle coated surfaces over 100 nm thin film surface are used in this experimentation. The surfaces are synthesized and fabricated by simple and cost-effective electron beam evaporation method. The test surfaces were characterized by scanning electron microscope and atomic force microscope to uncover the formation of crystalline structure on coated surfaces. These surfaces are utilized in pool boiling test rig using refrigerant R134a at 10 degrees C saturation temperatures. The result indicated that a maximum of 87.5% augmentation in the boiling heat transfer has been achieved by higher thickness of TiO2 coated surface than the bare copper surface. In addition, the incipience wall superheat is reduced for higher thickness coated surface. The augmentation of heat transfer coefficient might be the reason for increase in micro/nano-porosity, active nucleation site density and surface area of the heating surface. It is observed that with the increase of sub-cooling temperature of liquid, the bubble departure diameter was reduced while the heat transfer coefficient has been increased.