A new technique for distributed estimation and control of large-scale systems is presented in this paper. The proposed method makes use of a set of agents that implement local H-infinity controllers and Luenberger-like observers, improved with consensus-based corrections that incorporate information received from other agents. The communication between agents is assumed to be unreliable, this is modelled by time-varying delays and packet dropouts. The proposed methodology is an application for a class of nonlinear system affected by external disturbances. Some simulations are presented to illustrate the performance of this technique compared to the centralised case.