This study provided an estimate of the potential of bio-hydrogen production from dark fermentation of crop residues on a worldwide scale. The different crop residues reviewed included sugarcane tops, leaves and bagasse, corn straw, corn cob and corn stover, wheat straw, rice straw and husk, soybean straw, oil palm trunk and empty fruit bunch, sugar beet pulp, cassava residue, barley straw and sweet sorghum bagasse. Among these crop residues, wheat and rice straws are produced in the highest amount although sugarcane dominates crop production on a worldwide scale. Based on the bio-hydrogen yields reported in literature, estimated worldwide bio-hydrogen potential is highest for untreated rice straw at 58,002 Mm(3)/year followed by untreated wheat straw at 34,680 Mm(3)/year. This corresponds to a bio-energy potential of 623 PJ/year and 373 PJ/year for raw rice straw and wheat straw respectively while pre-treatment of the crop residues significantly increases the bio-hydrogen and bio-energy potential. While dark fermentation of crop residues offers a huge bio-energy potential, the process suffers from several constraints that hinder its implementation. As such, coupling of the dark fermentation process with the anaerobic digestion process as a two-stage process seems the most economically viable option for large-scale implementation. (C) 2018 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.