To study the effect of surfactant on the resistance of wall-bound flow, the adsorption and aggregation behaviors of surfactant fluid on both smooth and groove- patterned rough surface are investigated through many-body dissipative particle dynamics (MDPD) simulation. The MDPD models of surfactants were carefully parametrized and have been validated to be able to simulate the aggregation and adsorption behavior of surfactants. The simulation results show that the surfactant in laminar flow can only increase the flow resistance on the smooth surface. On the rough surface, surfactant with strong adsorption performance on the channel wall shows a drag reduction effect at moderate concentration. The surfactant with weak adsorption properties can enhance the flow resistance, which is even more significant than that of those surfactants with no adsorption capacity. Although heating (high temperature) can generally reduce the viscosity and flow resistance of surfactant fluid, it would cause a poor drag reduction efficiency. It may arise from the destruction of the adsorption layer and the interruption of the fluid/boundary interface. Surfactant adsorption can tune the roughness of the fluid boundary on either the smooth or rough surface in a different manner, which turns out to be highly correlated to the change in flow resistance. Compared with the adsorption layer, surfactant in the bulk fluid makes a greater contribution to enhancing the flow resistance as the concentration rises. This study is expected to be helpful in guiding the application of surfactants on the micro- and nanoscale such as lab-on-a-chip nanodevices and EOR in a low-permeability porous medium.