Structure of strongly turbulent premixed n-dodecane/air flames with high Karlovitz numbers (Ka) is studied based on three-dimensional (3D) direct numerical simulation (DNS) datasets. Heat release and fuel consumption rates in these flames are observed to be enhanced compared to what can be conventionally described as increases in flame surface area. To explain the cause for the burning rate enhancement, temperature and species mass fractions are first investigated to reveal the overall flame structure. The chemical explosive mode analysis (CEMA) is then employed to identify local combustion modes, including local assisted ignition, auto-ignition, and extinction, each of which is found to play a role in the overall burning rates. The spatial distribution of the local modes is found to be drastically different from that in comparable laminar flames where the local extinction mode is mostly absent. For the high-Ka cases (Ka = 10(3) and 10(4)), the extinction mode is shown to be comparable to or more important than the auto-ignition mode for heat release and fuel consumption rates. In contrast, the auto-ignition mode plays a more important role in heat release than the extinction mode in laminar and the relatively low-Ka flames (Ka = 10(2)). In addition, two types of mixture pockets are identified by CEMA: pockets of reactants in bulk products and pockets of hot products in bulk reactants. The dynamics of these pockets are strongly affected by the local modes of the spatially adjacent mixtures. While the pockets of reactants in bulk products are almost always consumed by auto-ignition and/or inward flame propagation, the pockets of products in bulk reactants may either grow themselves due to outward flame propagation or contract volumetrically due to local extinction. In contrast to the conventional understanding, local extinction can promote the overall burning process, as it enables mixing of the radicals and sensible energy from the product pockets into the surrounding reactants, thus facilitating their ignition. Clearly, such effects must be considered in order to closely model these flames. (C) 2019 The Combustion Institute. Published by Elsevier Inc. All rights reserved.