In this paper, TiO2/InVO(4)n-n nanoheterojunctions with enhanced gas sensing performance were successfully synthesized. The TiO2/InVO4-based sensor exhibits relatively low optimum operating temperature of 250 degrees C, at which the sensitivity and response/recovery time are 30.5 and 10/10 s, respectively, to 100 ppm ammonia gas. The effective detection (R-a/R-g = 1.7) to 1 ppm ammonia signifies the low detection limit of the sensor. Moreover, the sensor possesses evident room temperature response (R-a/R-g = 3.0, 100 ppm) to ammonia gas. Based on these, the enhanced sensing mechanisms of TiO2/InVO4 have been discussed in-depth, which can be ascribed to the synergistic effects of eximious absorption kinetics, outstanding carrier dynamics, unique nanoheterojunction structure and excellent catalytic property. This provides a meaningful guidance for the subsequent nanoheterojunction construction for excellent gas sensor.