This paper presents an extensive uniflow cyclone dedusting study and analysis of respective performance data based on separation efficiency, pressure drop and cut size. A laboratory-scale uniflow cyclone with axial swirl vanes is used to test a range of setups employed by the industry. The most important swirl vane and vortex finder parameters, as well as concentration levels are examined in detail with reference to geometric changes. Comprehensive separation data is provided, showing the impact of angle of attack, core size ratio, blade overlap, vortex finder length and vortex finder diameter on performance levels. Grade efficiency curves and cut sizes for each setup are analyzed. A cut size below 4 mu m is achieved for marble dust with a particle density of 2700 kg m(-3). Results show that the cut size can be reduced by over 50% with an increase of pressure drop by approximately 30% in relation to the base configuration. For a steep angle of attack of 15 degrees and a core size ratio of 0.125, the cut size can be reduced by 25%, with a 35% reduction of pressure drop. (C) 2019 Elsevier B.V. All rights reserved.