Vortex ropes occurred in the draft tube when hydraulic turbines operating at off-design conditions, which can generate pressure fluctuations. Cavitation vortex rope is one of the most harmful factors to the safety of hydroturbines which may induce further pressure fluctuations. A study of the multiphase flow in a model turbine is presented in this paper using the software ANSYS CFX. The main emphasis is spending on understanding the mechanism of cavitation evolution and underlying its correlation mechanism with flow instabilities. The results indicate that two types of pressure variations can be captured with a cavitation rope: 1) The type due to the vortex rope rotating whose frequency is 1/5-1/4 times runner rotating frequency; 2) The type due to cavitation volume surge, whose frequency is less than that of vortex rope rotating. The frequency of pressure fluctuation due to cavitation keep contanst as the cavitation number decreases, while the amplitude much increases. While the frequency and amplitude of the pressure variation caused by votex rope rotating increase a little. Based on vorticity transport equation, the vortex and cavitation have a close relation. Cavitation increases the vortex production as well as the pressure fluctuation frequency caused by the rotation of vortex rope. (C) 2019 Elsevier Ltd. All rights reserved.