During the past two decades, research on membrane and membrane-based separation process has developed rapidly in water treatment, gas separation, biomedicine, biotechnology, chemical manufacturing and separation process integration. In China, remarkable progresses on membrane preparation, process development and industrial application have been made with the burgeoning of the domestic economy. This review highlights the recent development of advanced membranes in China, such as smart membranes for molecular-recognizable separation, ion exchange membrane for chemical productions, antifouling membrane for liquid separation, high-performance gas separation membranes and the high-efficiency hybrid membrane separation process design, etc. Additionally, the applications of advanced membranes, relevant devices and process design strategy in chemical engineering related fields are discussed in detail. Finally, perspectives on the future research directions, key challenges and issues in membrane separation are concluded.