Brazil is the largest producer of sugarcane ethanol in the world. Among the technologies that aim to improve the process, second generation ethanol is one of the most promising. Although still in development, it is a consensus that this process must be integrated into the production of first generation ethanol. Most of the work on this subject is involved in evaluating the steady-state process. However, the knowledge of the process dynamics plays an important role on the operational efficiency and control. In this work multiple effect evaporation is addressed. A dynamic phenomenological model of this step was developed in EMSO process simulator. A stream of glucose syrup is mixed with sugarcane juice stream at the entrance of the system and simulations were performed to analyze the integrated system dynamics. Step disturbances were applied in the sugar concentration, volumetric flow rate and temperature of the juice individually and simultaneously. Glucose syrup concentration and flow rate was also disturbed. PI/PID controllers were tested in order to control the system and the model consistency was verified in Aspen Dynamics. The analysis suggests that an adequate control system at the liquid and vapor output of each vessel cannot be achieved using only classical controllers. (C) 2019 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.