The MoS2/Ti3C2 catalyst with a unique sphere/sheet structure were prepared by hydro thermal method. The MoS2/Ti3C2 heterostructure loading 30% Ti3C2 has a maximum hydrogen production rate of 6144.7 mu mol g(-1) h(-1), which are 2.3 times higher than those of the pure MoS2. The heterostructure maintains a high catalytic activity within 4 cycles. The heterostructure not only effectively reduce the recombination of photogenerated electrons and holes, but also provide more activation sites, which promotes the photocatalytic hydrogen evolution reaction (HER). These works can provide reference for the development of efficient catalysts in photocatalytic hydrogen evolution. (C) 2019 Published by Elsevier Ltd on behalf of Hydrogen Energy Publications LLC.