Two-dimensional flaky magnesium-aluminum hydrotalcite (Mg-Al-LDHs) with uniform particle size distribution and high dispersion was prepared using a supergravity rotating bed. The samples were characterized by scanning electron microscopy, X-ray diffraction, Brunauer-Emmett-Teller, particle size distribution analyzer (PSDA), and so forth. The morphology and particle size distribution of the Mg-Al-LDHs that were prepared by traditional hydrothermal synthesis (T-Mg-Al-LDHs) and the supergravity rotating bed (S-Mg-Al-LDHs) were compared. The adsorption performance of these Mg-Al-LDHs prepared by two methods and their calcined products (T-Mg-Al-LDOs and S-Mg-Al-LDOs) for chloride ions was also investigated. The results showed that the dispersed uniform two-dimensional Mg-Al-LDHs could be prepared using the supergravity rotating bed system, which had regularly and uniformly distributed morphology and can easily form a cross between support structures. The specific surface area of S-Mg-Al-LDHs was 142.623 m(2)/g, which is much larger than that of T-Mg-Al-LDHs (115.311 m(2)/g). The saturation absorbance of S-Mg-Al-LDHs and S-Mg-Al-LDOs toward chloride ions is 34.82 and 108.06 mg/g, respectively; the saturation absorbance of T-Mg-Al-LDHs and T-Mg-Al-LDOs toward chloride ions is 24.72 and 96.07 mg/g, respectively, which shows that S-Mg-Al-LDHs and S-Mg-Al-LDOs exhibit excellent adsorption performance. The adsorption kinetics and adsorption isotherms of S-Mg-Al-LDOs can be well-described by the pseudo-secondorder kinetic and Langmuir isotherm.