It is of great significance to develop highly efficient and robust oxygen evolution reaction (OER) electrocatalysts derived from earth-abundant and inexpensive elements for future hydrogen economy via electrochemical water splitting. Herein, Cu-based metal-organic framework (MOP) is directly supported on conductive Cu foam (CF) by a simply chemical oxidation of Cu substrate to grow Cu(OH)(2) nanowire arrays, followed by solvothermal treatment to obtain in situ grown Cu-based MOF electrode (MOF [Cu(OH)(2)]/CF). The as-prepared 3D electrode shows superior OER activity with a low potential of 330 mV to deliver a current density of 10 mA cm(-2), a Tafel slope of 108 mV dec(-1), and excellent durability in alkaline media (1.0 M KOH). After electrolysis, XRD confirms that the initial MOFs have been transformed into CuO species, which are essentially active components for OER performance. This demonstrates that the MOFs can serve as efficient precursors for formation of highly active Cu oxide catalysts towards OER. This work provides a new strategy to develop MOFs-derived electrocatalysts for future clean energy conversion and storage systems. (C) 2020 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.