Polydopamine (PDA) is well-known as the first material-independent adhesive, which firmly attaches to various substances, even hydrophobic materials, through strong coordinative interactions between the phenolic hydroxyl groups of PDA and the substances. In contrast, oil-infused materials such as self-lubricating gels (SLUGs) exhibit excellent antiadhesive properties against viscous liquids, ice/snow, (bio)fouling, and so on. In this study, we simply questioned: "What will happen when these two materials with contrary nature meet"? To answer this, we formed a PDA layer on a SLUG surface that exhibits thermoresponsive syneretic properties (release of liquid from the gel matrix to the outer surface) and investigated its interfacial behavior. The oil layer caused by syneresis from the SLUGs at -20 degrees C was found to show resistance to adhesion of universally adhesive PDA.