This article is aimed to design new antioxidant phyto-nanosystems based on liposomes and vegetal extracts of sage (Salvia officinalis L.) and mint (Mentha piperita L.). The lipid vesicles were obtained by thin film hydration method, and vegetal extracts of sage or mint were incorporated both in hydrophobic and in aqueous compartments of these lipid systems. The obtained phyto-containing liposomes were characterized by UV-Vis absorption and dynamic light scattering (DLS) measurements, and their antioxidant activity was assessed through chemiluminescence technique. The obtained artificial lipid bilayers loaded with phyto-extracts exhibited impressive antioxidant properties.