Fused filament fabrication is considered one of the most used processes in additive manufacturing rapid prototypes out of polymeric material. Poor strength of the deposited layers is still one of the main critical problems in this process, which affects the mechanical properties of the final parts. To improve the mechanical strength, investigation into various process parameters must be considered. In this article, the influence of different process parameters has been experimentally investigated by means of physicochemical and mechanical characterizations. Special attention was given to the thermal aspect. In that respect, the in situ measurement of temperature profile during deposition indicated that several parameters affect the cooling rate of material and consequently have an influence on the final parts. It was found that the influence of increasing the extruder temperature is more significant in comparison with other process parameters.