화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.29, No.1, 2-14, January, 2021
DOI10.1007/s13233-021-9011-x  Export Citation
Peptide Materials for Smart Therapeutic Applications
Jeonghun Lee1, and Chulhee Kim1, 2, †
  • 1Department of Polymer Science and Engineering, Inha University, Incheon 22212, Korea
  • 2Program in Environmental and Polymer Engineering, Inha University, Incheon 22212, Korea
E-mail:
Myriad peptides have been reported for utilization as key motives in design of smart therapeutic materials due to their capabilities for selective binding, self-assembly, and bioresponsiveness. In this review, we describe various therapeutic applications of peptides, their derivatives, and their assemblies by employing the bioresponsive characteristics. Peptide materials have been developed for specific targeting or deep tissue penetration. Amphiphilic peptides and their self-assembled materials also have been adopted for the development of therapeutic materials. Furthermore, triggered structural transformation of the self-assemblies of peptides in response to various stimuli in biological environments facilitates diverse therapeutic applications of peptide materials.
Keywords:peptides;therapeutic materials;selective binding;self-assembled structures;stimuli-responsiveness
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