A study on the stability and sensitivity of mediator-based enzymatic glucose sensor measured by catalyst consisting of multilayer stacked via layer-by-layer

Joonyoung Lee; Kyuhwan Hyun; Yongchai Kwon

Journal of Industrial and Engineering Chemistry, Vol.93, 383-387, January, 2021

DOI10.1016/j.jiec.2020.10.015 Export Citation

A study on the stability and sensitivity of mediator-based enzymatic glucose sensor measured by catalyst consisting of multilayer stacked via layer-by-layer

Joonyoung Lee¹, Kyuhwan Hyun¹, and Yongchai Kwon^{1, 2, †}

¹Graduate school of Energy and Environment, Seoul National University of Science and Technology, 232 Gongneung-ro, Nowon-gu, Seoul 01811, Republic of Korea
²Department of Chemical and Biomolecular Engineering, Seoul National University of Science and Technology, 232 Gongneung-ro, Nowon-gu, Seoul 01811, Republic of Korea

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A catalyst consisting of carbon nanotube, 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO), polyacrylic acid (PAA), polyethylenimine (PEI), and glucose oxidase (GOx) (CNT/[TEMPO-PAA]/PEI/GOx) is developed to improve the stability and sensitivity of mediator based glucose sensor. In this catalyst, TEMPO is bonded with PAA to prevent the leaching out of TEMPO, which plays a crucial role in increasing the glucose sensitivity by instilling charges in it. The TEMPO-PAA composite is then linked to other components by electrostatic force. To confirm the chemical structure of the catalyst, its chemical bonds and surface charge are investigated by Fourier-transform infrared spectroscopy and zeta potential. When the stability and glucose sensitivity are measured, this catalyst preserves 80% of its initial catalytic activity for one week although other similar catalysts show far worse stability. In addition, the linear relationship of glucose concentration and reactivity of glucose oxidation shown in 1-10 mM glucose range that corresponds to actual blood glucose concentration of human being indicates that this catalyst can induce excellent glucose sensitivity. In terms of selectivity, this catalyst reacts with blood glucose highly selectively, whereas this is not reacted with other eight different saccharides.

Keywords:Glucose sensor;2,2,6,6-Tetramethylpiperidine 1-oxyl;Polyacrylic acid;Polyethylenimine;Glucose oxidase

[References]

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Lee H, Hong YJ, Baik S, Hyeon T, Kim DH, Adv. Healthc. Mater., 7, 1 (2018)
Ali H, Bensaali F, Jaber F, IEEE Access., 5, 9163 (2017)
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Christwardana M, Ji JY, Chung YJ, Kwon YC, Korean J. Chem. Eng., 34(11), 2916 (2017)
Atanassov P, Apblett C, Banta S, Brozik S, Barton SC, Cooney M, Liaw BY, Mukerjee S, Minteer SD, Interface-Electrochem. Soc., 16, 28 (2007)
Christwardana M, Chung YJ, Kwon YC, Korean J. Chem. Eng., 34(11), 3009 (2017)
Christwardana M, Chung YJ, Kim DH, Kwon YC, J. Ind. Eng. Chem., 71, 435 (2019)
Sheng Q, Zhang D, Wu Q, Zheng J, Tang H, Anal. Methods, 7, 6896 (2015)
Pang P, Zhang Y, Ge S, Cai Q, Yao S, Grimes CA, Sens. Actuators B-Chem., 136, 310 (2009)
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Gunasingham H, Tan CH, Analyst, 115, 35 (1990)
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Barton SC, Gallaway J, Atanassov P, Chem. Rev., 104(10), 4867 (2004)
Christwardana M, Kim DH, Chung Y, Kwon Y, Appl. Surf. Sci., 429, 180 (2018)
Gooding JJ, Electrochim. Acta, 50(15), 3049 (2005)
Hyun K, Han SW, Koh WG, Kwon Y, Int. J. Hydrog. Energy, 40(5), 2199 (2015)
Chung Y, Hyun KH, Kwon Y, Nanoscale, 8, 1161 (2016)
Takahashi S, Aikawa Y, Kudo T, Ono T, Kashiwagi Y, Anzai JI, Colloid Polym. Sci., 292, 771 (2014)
Hyun KH, Han SW, Koh WG, Kwon Y, J. Power Sources, 286, 197 (2015)
Christwardana M, Chung Y, Kwon Y, NPG Asia Mater., 9, e386 (2017)
Ruff A, Curr. Opin. Electrochem., 5, 66 (2017)
Khan H, Kim CM, Kim SY, Goel S, Dwivedi PK, Sharma A, Kim YH, Kim GM, Int. J. Precis. Eng. Manuf. Technol., 6, 511 (2019)
Fontinha IR, Salta MM, Zheludkevich ML, Ferreira MGS, Port. Electrochim. Acta, 31, 307 (2013)
Yi X, Xu Z, Liu Y, Guo X, Ou M, Xu X, RSC Adv., 7, 6278 (2017)
Tamang S, Synth ‘ese et fonctionnalisation des nanocristaux’ emettant dans le proche infrarouge pour l’ imagerie biologique Sudarsan Tamang To cite this version: HAL Id: tel-00665109, (2017).
Hyun KH, Kang SY, Kwon YC, Korean J. Chem. Eng., 36(3), 500 (2019)
Christwardana M, Kwon Y, J. Power Sources, 299, 604 (2015)
Bollella P, Gorton L, Ludwig R, Antiochia R, Sensors, 17 (2017)
Ahn Yeonjoo, Yoo Kye Sang, Kim Lae-Hyun, Kwon Yongchai, Int. J. Hydrog. Energy, 41(39), 17548 (2016)

[Referenced By]

[1] International Diabetes Federation, IDF Diabetes Atlas Ninth, (2019).

[2] Lee H, Hong YJ, Baik S, Hyeon T, Kim DH, Adv. Healthc. Mater., 7, 1 (2018)

[3] Ali H, Bensaali F, Jaber F, IEEE Access., 5, 9163 (2017)

[4] Devadhasan JP, Kim S, Analyst, 137, 3917 (2012)

[5] Christwardana M, Ji JY, Chung YJ, Kwon YC, Korean J. Chem. Eng., 34(11), 2916 (2017)

[6] Atanassov P, Apblett C, Banta S, Brozik S, Barton SC, Cooney M, Liaw BY, Mukerjee S, Minteer SD, Interface-Electrochem. Soc., 16, 28 (2007)

[7] Christwardana M, Chung YJ, Kwon YC, Korean J. Chem. Eng., 34(11), 3009 (2017)

[8] Christwardana M, Chung YJ, Kim DH, Kwon YC, J. Ind. Eng. Chem., 71, 435 (2019)

[9] Sheng Q, Zhang D, Wu Q, Zheng J, Tang H, Anal. Methods, 7, 6896 (2015)

[10] Pang P, Zhang Y, Ge S, Cai Q, Yao S, Grimes CA, Sens. Actuators B-Chem., 136, 310 (2009)

[11] Ghabach M, Davarpanah AH, Lancet Gastroenterol. Hepatol., 5, 418 (2020)

[12] Grattieri M, Minteer SD, ACS Sensors, 3, 44 (2018)

[13] Cass AEG, Davis G, Francis GD, Allen H, Hill O, Aston WJ, Higgins IJ, Plotkin EV, Scott LDL, Turner APF, Anal. Chem., 56, 667 (1984)

[14] Gunasingham H, Tan CH, Analyst, 115, 35 (1990)

[15] Charbgoo F, Mirshahi M, Sarikhani S, Peroxidase Complex to Enhance Sensitivity of Immunodetection, (2012).

[16] Barton SC, Gallaway J, Atanassov P, Chem. Rev., 104(10), 4867 (2004)

[17] Christwardana M, Kim DH, Chung Y, Kwon Y, Appl. Surf. Sci., 429, 180 (2018)

[18] Gooding JJ, Electrochim. Acta, 50(15), 3049 (2005)

[19] Hyun K, Han SW, Koh WG, Kwon Y, Int. J. Hydrog. Energy, 40(5), 2199 (2015)

[20] Chung Y, Hyun KH, Kwon Y, Nanoscale, 8, 1161 (2016)

[21] Takahashi S, Aikawa Y, Kudo T, Ono T, Kashiwagi Y, Anzai JI, Colloid Polym. Sci., 292, 771 (2014)

[22] Hyun KH, Han SW, Koh WG, Kwon Y, J. Power Sources, 286, 197 (2015)

[23] Christwardana M, Chung Y, Kwon Y, NPG Asia Mater., 9, e386 (2017)

[24] Ruff A, Curr. Opin. Electrochem., 5, 66 (2017)

[25] Khan H, Kim CM, Kim SY, Goel S, Dwivedi PK, Sharma A, Kim YH, Kim GM, Int. J. Precis. Eng. Manuf. Technol., 6, 511 (2019)

[26] Fontinha IR, Salta MM, Zheludkevich ML, Ferreira MGS, Port. Electrochim. Acta, 31, 307 (2013)

[27] Yi X, Xu Z, Liu Y, Guo X, Ou M, Xu X, RSC Adv., 7, 6278 (2017)

[28] Tamang S, Synth ‘ese et fonctionnalisation des nanocristaux’ emettant dans le proche infrarouge pour l’ imagerie biologique Sudarsan Tamang To cite this version: HAL Id: tel-00665109, (2017).

[29] Hyun KH, Kang SY, Kwon YC, Korean J. Chem. Eng., 36(3), 500 (2019)

[30] Christwardana M, Kwon Y, J. Power Sources, 299, 604 (2015)

[31] Bollella P, Gorton L, Ludwig R, Antiochia R, Sensors, 17 (2017)

[32] Ahn Yeonjoo, Yoo Kye Sang, Kim Lae-Hyun, Kwon Yongchai, Int. J. Hydrog. Energy, 41(39), 17548 (2016)