The nucleation kinetics of the alpha form ofp-aminobenzoic acid from ethanolic and aqueous solutions is examined through a comparative examination of temperature-jump and anti-solvent drown-out isothermal crystallization methodologies. Analysis of the data reveals the measured induction times, and the calculated effective interfacial tensions as a function of the supersaturation show broadly equivalent behavior for the aqueous-ethanol mixed-solvent drown-out and temperature-jump ethanol solution systems, confirming the comparability of the two methodologies. The results also demonstrate poorer agreement with the temperature-jump pure aqueous system, highlighting the importance of the strength of solvation/desolvation as the key rate-limiting process for the overall nucleation behavior.