Presented here are two titanium-based metal-organic frameworks (Ti-MOFs) based on well-defined [Ti6Cu6(mu(3)-O)(2)(mu(2)-O)(9)(HSO4)(2)(SO4)(6)], which can be easily obtained from a cheap Ti source and CuSO4 and exhibited interesting magnetic properties. Furthermore, this clusters can be isolated in pure phase. Numerous uncoordinated sites of SO4 and labile ligands on the Ti and Cu centers of this cluster make it a good candidate as a secondary building unit to construct various Ti-MOFs in the future.