The NiHPO4-Ni(OH)(2) nanowire-assembled bouquets were easily synthesized. Scanning electron microscopy and transmission electron microscopy show the NiHPO4-Ni(OH)(2) bouquets form through the organization of nanowires which arrange with certain direction. The electrocatalytic activities of NiHPO4-Ni(OH)(2)-GCE towards the oxidation of methanol and urea were studied in NaOH. The nanowire-assembled bouquets were modified on the surface of the glassy carbon electrode, leading to the increase on the surface area of the electrode, which in turn enhanced the current density and electrocatalytic performance for the oxidation of methanol and urea. It shows the potential applications for the utilization of these energy molecules. [GRAPHICS] .