The present work is focused on the hydrothermal fabrication of lanthanum (La)-based metal-organic frameworks (MOFs) with the linkers of benzene-1,4-dicarboxylic acid (BDC) and amine-functionalized BDC, namely, 2-aminobenzene-1,4-dicarboxylic acid (ABDC), which are abbreviated as LagBDC and La@ABDC, respectively. The developed La@BDC and La@ABDC MOF composites were utilized for defluoridation of water. The defluoridation capacities (DCs) of the La@BDC and La@ABDC MOF composites were found to be 4920 and 4950 mgF(-)kg(-1), respectively. The influencing parameters of adsorption method, such as contact time, initial fluoride solution, MOF dosage, adsorbate pH, rivalry anions, and temperature, were investigated by batch scale. The structural and surface properties of the synthesized La@BDC and La@ABDC MOF composites were explored by powder X- ray diffraction (PXRD), Fourier transform infrared (FTIR) spectroscopy, thermogravimetric analysis (TGA), Brunauer-Emmett-Teller (BET) analysis, scanning electron microscopy (SEM), transmission electron microscopy (TEM) with selected area electron diffraction (SAED), energy-dispersive X-ray analysis (EDAX), and X-ray photoelectron spectroscopy (XPS). The best-fit model was found for both isotherms and kinetic studies for fluoride adsorption onto La-based MOF composites. Thermodynamic studies show the endothermic and spontaneous nature of fluoride adsorption onto the La@BDC and La@ABDC MOF composites. Furthermore, the La@BDC and La@ABDC MOF composites possess greater DCs even after six cycles in recyclability studies. Effective field study reports showed that the La@BDC and La@ABDC MOF composites are exceptionally encouraging and innovative type of adsorbent materials for defluoridation of contaminated field water.