In this paper, we designed and prepared a novel metal organic framework (MOF)/holey graphene (HG) composites as electrode materials for electrochemistry and capacitive deionization (CDI). The MOF nanoparticles were attached to the surface of the HG sheets to form layered porous structure, which promoted the transport of ions and electrons in the electrode/electrolyte interfaces. Additionally, the synergistic effect of these composite electrodes, which combined pseudocapacitance performance of MOF and the high conductivity of graphene, contributed to enhancing the performance of electrochemistry and CDI. The MOF/HG-2 exhibited high capacitances of 526 F g(-1) at current rates of 0.1 A g(-1), low charge transfer resistance of 0.53 X, and excellent cycling stability (retention of about 90.3% after 5000 cycles at 2 A g(-1)). As electrode materials for CDI, the MOF/HG-2 displayed a remarkable electrosorption capacity of 39.6 mg g(-1) with initial salt concentration of 800 mg L-1, and there was no obvious attenuation after 20 CDI regeneration cycles. These results confirmed that MOF/HG was a promising electrode material for the actual application of CDI. (C) 2020 Elsevier Inc. All rights reserved.