화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Korean Journal of Chemical Engineering, Vol.38, No.5, 899-905, May, 2021
DOI10.1007/s11814-021-0774-8  Export Citation
Green and mild production of 5-aminolevulinic acid from algal biomass
Binglin Chen1, Jiachen Li1, Yunchao Feng1, Kai Le1, Yuxia Zai1, Xing Tang1, 2, Yong Sun1, 2, Xianhai Zeng1, 2, †, and Lu Lin1, 2
  • 1College of Energy, Xiamen University, Xiamen 361102, China
  • 2Fujian Engineering and Research Centre of Clean and High-valued Technologies for Biomass, Xiamen Key Laboratory of Clean and High-valued Utilization for Biomass, Xiamen 361102, China
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Algal biomass was converted into 5-aminolevulinic acid (5-ALA) in five chemical steps: conversion to 5-(chloromethyl)furfural (5-CMF), ammoniation, ring-opening (photo-oxidation), reduction, and hydrolyzation. Among them, we mainly focused on the 5-CMF production and the following ammoniation. To our knowledge, the mixed solvent catalytic system of deep eutectic solvent (DES) and low concentration hydrochloric acid is the first reported for the synthesis of 5-CMF from algal biomass, providing a 24.6% 5-CMF yield at 120 oC for 5 h. Potassium phthalimide (KPI) was employed as an ammoniation reagent with superb selectivity and activity instead of conventional sodium azide (NaN3). Optimizing the experimental design, a 23.7% 5-ALA yield along with high purity (>96%) was achieved from 5-CMF, and the total 5-ALA yield was 5.8% from algal biomass. This work provides a green and mild pathway for 5- ALA production from algal biomass.
Keywords:5-Aminolevulinic Acid;5-(Chloromethyl)furfural;Deep Eutectic Solvent;Ammoniation;Algal Biomass
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