Changes in the volume and value of org. and inorg. substances produced in Poland in 2007-2018 were presented. Based on the anal. of the available data, an increase in the prodn. of inorg. substances and a decrease in the prodn. of org. ones was obsd. As the org. substances are more toxic than the inorg. ones, the implementation of REACH resulted in a decrease in the prodn. of org. chemicals.