선택적 수용성 차수재 개발을 위한 나트륨-알지네이트/폴리아크릴아마이드 하이드로겔의 수용 속도 제어

최광묵; 최진주; 김우철; 황환민; 김명웅; 김민준; Gwang-Mook Choi; Jin-Ju Choi; Woo-Cheol Kim; Hwanmin Hwang; Myungwoong Kim; Min-Jun Kim

Polymer(Korea), Vol.45, No.6, 841-848, November, 2021

DOI10.7317/pk.2021.45.6.841 Export Citation

선택적 수용성 차수재 개발을 위한 나트륨-알지네이트/폴리아크릴아마이드 하이드로겔의 수용 속도 제어

Control of Dissolution Rate of Sodium-Alginate/Polyacrylamide Hydrogel for Selectively Dissolvable Water-Blocking Device

최광묵^†, 최진주, 김우철¹, 황환민², 김명웅², 김민준^†

고등기술연구원 신소재공정센터
¹한국지역난방공사 미래개발원
²인하대학교 화학·화학공학 융합학과

Gwang-Mook Choi^†, Jin-Ju Choi, Woo-Cheol Kim¹, Hwanmin Hwang², Myungwoong Kim², and Min-Jun Kim^†

Advanced Materials & Processing Center, Institute for Advanced Engineering, Yongin 17180, Korea
¹R & D Institute, Korea District Heating Corp., Yongin 17099, Korea
²Department of Chemistry and Chemical Engineering, Inha University, Incheon 22212, Korea

E-mail:,

초록

본 연구에서는 나트륨-알지네이트/폴리아크릴아마이드(SA/PAM) 하이드로겔의 온도 및 가교제로 작용하는 N,N′-메틸렌비스아크릴아마이드(MBAAm) 농도에 따른 수용 형태 및 시간 변화를 분석하였다. 실험 결과, 수온이 증가하거나 가교제 농도가 감소할수록 SA/PAM 하이드로겔의 팽윤 및 수용 속도가 증가함을 확인하였다. 수온 상승 시 이온결합이 불안정하고 아마이드 결합이 깨지면서 하이드로겔의 수용 속도를 증가시키는 반면, MBAAm의 밀도 감소 시에는 주요 결합력인 이온결합력이 약화되어 고온수에 취약함을 확인하였다. 본 연구를 통해 SA/PAM 하이드로겔의 수용속도의 제어가 가능함을 증명하였고 선택적 수용이 가능한 차수재로서의 가능성을 제시하였다.

The objective of this study was to examine changes in the dissolution rate of sodium-alginate/polyacrylamide (SA/PAM) hydrogel according to water temperature and concentration of cross-linking agent N,N'-methylenebisacrylamide (MBAAm). Results confirmed that swelling and dissolution rates of the SA/PAM hydrogel were increased when the temperature of the water was increased or the amount of MBAAm was decreased. When water temperature was increased, ionic crosslinks became unstable and amide bonds were broken due to hydrolysis, causing the hydrogel to rapidly dissolve in the hot water. Also, after the amount of MBAAm was decreased, ionic crosslinks became dominant and SA/PAM hydrogel became more vulnerable to hot water. Here, we analyzed the dissolution rate of hydrogel following temperature and MBAAm density changes. We also developed a selectively dissolvable water-blocking hydrogel that could be stable in cold water and become dissolved quickly in hot water.

Keywords:sodium-alginate/polyacrylamide hydrogel;dissolution rate;temperature effect;cross-linking density effect;selectively dissolvable water-blocking material

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[2] Liu S, Li L, ACS Appl. Mater. Interfaces, 9, 26429 (2017)

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[6] Guo H, Jiao T, Zhang Q, Guo W, Peng Q, Yan X, Nanoscale Res. Lett., 10, 272 (2015)

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[8] Yi XX, Xu ZZ, Liu YY, Guo XX, Ou MM, Xu XX, RSC Adv., 7, 6278 (2017)

[9] Yi JQ, Nguyen KCT, Wang WD, Yang WS, Pan MF, Lou E, Major PW, Le LH, Zeng HB, J. Colloid Interface Sci., 578, 598 (2020)

[10] Ruland A, Gilmore KJ, Daikuara LY, Fay CD, Yue Z, Wallace GG, Acta Biomater., 91, 173 (2019)

[11] Jiang H, Carter NM, Zareei A, et al., ACS Appl. Bio Mater., 3, 4012 (2020)

[12] Jiang H, Carrillo KT, Kobayashi T, Sonochem., 32, 398 (2016)

[13] Neethu TM, Dubey PK, Kaswala AR, Int. J. Curr. Microbiol. App. Sci., 7, 3155 (2018)

[14] El-Asmar J, Jaafar H, Bashour I, Farran MT, Saoud IP, Clean-Soil Air Water, 45, 170025 (2017)

[15] Saha A, Rattan B, Sekharan S, Manna U, Geoderma, 368, 114310 (2020)

[16] Zhu J, Hu J, Marchant RE, Biomimetic Biomaterials, pp238, 2013.

[17] Xiong G, Luo H, Gu F, Zhang J, Hu D, Wan YA, J. Biomater. Nanobiotechnol., 4, 316 (2013)

[18] McKinnon DD, Kloxin AM, Anseth KS, Biomater. Sci., 1, 460 (2013)

[19] Rustad KC, Wong VW, Sorkin M, Glotzbach JP, Major MR, Rajadas J, Longaker MT, Gurtner GC, Biomaterials, 33, 80 (2012)

[20] Serban BA, Barrett-Catton E, Serban MA, Gels, 6, 38 (2020)

[21] Zuckerman ST, Rivera-Delgado E, Haley RM, Korley JN, von Recum HA, Gels, 6, 9 (2020)

[22] Sun JY, Zhao X, Illeperuma WRK, Chaudhuri O, Oh KH, Mooney DJ, Vlassak JJ, Suo Z, Nature, 489, 133 (2012)

[23] Darnell MC, Sun JY, Mehta M, Johnson C, Arany PR, Suo Z, Mooney DJ, Biomaterials, 34, 8042 (2013)

[24] Chavda HV, Patel CN, Int. J. Pharm. Investig., 1, 17 (2011)

[25] Meyer A, Jones N, Lin Y, Kranbuehl D, Macromolecules, 35(7), 2784 (2002)

[26] Matsushima K, Minoshima H, Kawanami H, Ikushima Y, Nishizawa M, Kawamukai A, Hara K, Ind. Eng. Chem. Res., 44(25), 9626 (2005)

[27] Smith RM, Hansen DE, J. Am. Chem. Soc., 120(35), 8910 (1998)