Antimicrobial Evaluation and Characterization of Copper Nanoparticles Synthesized by the Simple Chemical Method

Arshad Hussain Wazir; Qudratullah Khan; Nisar Ahmad; Faizan Ullah; Imdadullah Quereshi; Hazrat Ali

Korean Journal of Materials Research, Vol.32, No.2, 80-84, February, 2022

DOI10.3740/MRSK.2022.32.2.80 Export Citation

Antimicrobial Evaluation and Characterization of Copper Nanoparticles Synthesized by the Simple Chemical Method

Arshad Hussain Wazir^†, Qudratullah Khan¹, Nisar Ahmad¹, Faizan Ullah², Imdadullah Quereshi, and Hazrat Ali³

Carbon Materials Laboratory, Department of Chemistry, University of Science and Technology Bannu, Bannu, Khyber Pukhtunkhwa 28100, Pakistan
¹Department of Biotechnology, University of Science and Technology Bannu, Bannu, Khyber Pukhtunkhwa 28100, Pakistan
²Department of Botany, University of Science and Technology Bannu, Bannu, Khyber Pakhtunkhawa 28100, Pakistan
³Department of Chemistry, University of Mianwali, Punjab, Pakistan, Pakistan

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Copper nanoparticles (CuNPs) are considered of great importance due to their high catalytic and antimicrobial activities. This study focuses on the preparation and characterization of CuNPs, and on their antibacterial/antifungal activities. A copper salt (copper sulfate pentahydrate) as precursor, starch as stabilizing agent, and ascorbic acid as reducing agent were used to fabricate CuNPs. The resulting product was characterized via different techniques such as X-ray diffractrometry (XRD), Fourier Transform Infrared (FTIR) spectroscopy, and Scanning electron microscopy (SEM) to confirm its characteristic properties. Employing the Scherrer formula, the mean crystallite sizes of copper (Cu) and cuprous oxide (Cu2O) nanocrystals were found to be 29.21 and 25.33 nm, respectively, as measured from the main X-ray diffraction peaks. The functional groups present in the resulting CuNPs were confirmed by FTIR. In addition, the engineered CuNPs showed antibacterial and antifungal activity against tested pathogenic bacterial and fungal strains.

Keywords:copper nanoparticles;synthesis;chemical reduction;characterization;antimicrobial activity

[References]

Tatariants M, Yousef S, Sakalauskaitė S, Daugelavičius R, Denafas G, Bendikiene R, Waste Manage., 78, 521 (2018)
Suramwar NV, Thakare SR, Khaty NT, Arabian J. Chem., 9, S1807 (2016)
Ramyadevi J, Jeyasubramanian K, Marikani A, Rajakumar G, Rahuman AA, Mater. Lett., 71, 114 (2012)
Rafique M, Shaikh AJ, Rasheed R, Tahir MB, Bakhat HF, Rafique MS, Rabban F, Nano, 12, 1750043 (2017)
Khan A, Rashid A, Younas R, Chong R, Int. Nano Lett., 6, 21 (2016)
Vilar-Vidal N, Blanco MC, Lopez-Quintela MA, Rivas J, Serra C, J. Phys. Chem. C, 114, 15924 (2010)
Umer A, Naveed S, Ramzan N, Rafque MS, Nano, 7, 1230005 (2012)
Yadav TP, Yadav RM, Singh DP, Nanosci. Nanotechnol., 2, 22 (2012)
Yamaguchi A, Okada I, Fukuoka T, Sakurai I, Utsumi Y, Jpn. J. Appl. Phys., 55, 055502 (2016)
Effenberger FB, Sulca MA, Machini MT, Couto RA, Kiyohara PK, Machado G, Rossi LM, J. Nanopart. Res., 16, 1 (2014)
Dang TM, Le TT, Fribourg-Blanc E, Dang MC, Adv. Nat. Sci. Nanosci. Nanotechnol., 2, 015009 (2011)
Olad A, Alipour M, Nosrati R, Bull. Mater. Sci., 40, 1013 (2017)
Gawande MB, Goswami A, Felpin FX, Asefa T, Huang X, Silva R, Zou X, Zboril R, Varma RS, Chem. Rev., 116, 3722 (2016)
Perez C, Pauli M, Bazerque P, Acta Biol. Med. Exp., 15, 113 (1990)
Martis P, Fonseca A, Mekhalif Z, Delhalle J, J. Nanopart. Res., 12, 439 (2010)
Kouti M, Matouri L, Sci. Iran., 17, 73 (2010)
Aslam M, Gopakumar G, Shoba TL, Mulla IS, Vijayamohanan K, Kulkarni SK, Urban J, Vogel W, J. Colloid Interface Sci., 255, 79 (2002)
Feng L, Zhang C, Gao G, Cui D, Nanoscale Res. Lett., 7, 1 (2012)
Murugadoss G, Rajamannan B, Madhusudhanana U, Chalcogenide Lett., 6, 197 (2009)
Lee Y, Choi JR, Lee KJ, Stott NE, Kim D, Nanotechnology, 19, 415604 (2008)
Salavati-Niasari M, Davar F, Mater. Lett., 63, 441 (2009)
Umer A, Naveed S, Ramzan N, Rafique MS, Imran M, Matéria, 19, 197 (2014)
Suresh Y, Annapurna S, Bhikshamaiah G, Singh AK, Int. J. Sci. Eng. Res., 5, 156 (2014)
Raffi M, Mehrwan S, Bhatti TM, Akhter JI, Hameed A, Yawar W, Mahmood UHM, Ann. Microbiol., 60, 75 (2010)
Stoimenov PK, Klinger RL, Marchin GL, Klabunde KG, Langmuir, 18, 6679 (2002)
Mahmoodi S, Elmi A, Hallaj-Nezhadi S, J. Mol. Pharm. Org. Process Res, 6, 140 (2018)
Bayat M, Zargar M, Chudinova E, Astarkhanova T, Pakina E, Molecules, 26, 5402 (2021)
Oussou-Azo AF, Nakama T, Nakamura M, Futagami T, Vestergaard MCM, Nanomaterials, 10, 2 (2020)

[1] Tatariants M, Yousef S, Sakalauskaitė S, Daugelavičius R, Denafas G, Bendikiene R, Waste Manage., 78, 521 (2018)

[2] Suramwar NV, Thakare SR, Khaty NT, Arabian J. Chem., 9, S1807 (2016)

[3] Ramyadevi J, Jeyasubramanian K, Marikani A, Rajakumar G, Rahuman AA, Mater. Lett., 71, 114 (2012)

[4] Rafique M, Shaikh AJ, Rasheed R, Tahir MB, Bakhat HF, Rafique MS, Rabban F, Nano, 12, 1750043 (2017)

[5] Khan A, Rashid A, Younas R, Chong R, Int. Nano Lett., 6, 21 (2016)

[6] Vilar-Vidal N, Blanco MC, Lopez-Quintela MA, Rivas J, Serra C, J. Phys. Chem. C, 114, 15924 (2010)

[7] Umer A, Naveed S, Ramzan N, Rafque MS, Nano, 7, 1230005 (2012)

[8] Yadav TP, Yadav RM, Singh DP, Nanosci. Nanotechnol., 2, 22 (2012)

[9] Yamaguchi A, Okada I, Fukuoka T, Sakurai I, Utsumi Y, Jpn. J. Appl. Phys., 55, 055502 (2016)

[10] Effenberger FB, Sulca MA, Machini MT, Couto RA, Kiyohara PK, Machado G, Rossi LM, J. Nanopart. Res., 16, 1 (2014)

[11] Dang TM, Le TT, Fribourg-Blanc E, Dang MC, Adv. Nat. Sci. Nanosci. Nanotechnol., 2, 015009 (2011)

[12] Olad A, Alipour M, Nosrati R, Bull. Mater. Sci., 40, 1013 (2017)

[13] Gawande MB, Goswami A, Felpin FX, Asefa T, Huang X, Silva R, Zou X, Zboril R, Varma RS, Chem. Rev., 116, 3722 (2016)

[14] Perez C, Pauli M, Bazerque P, Acta Biol. Med. Exp., 15, 113 (1990)

[15] Martis P, Fonseca A, Mekhalif Z, Delhalle J, J. Nanopart. Res., 12, 439 (2010)

[16] Kouti M, Matouri L, Sci. Iran., 17, 73 (2010)

[17] Aslam M, Gopakumar G, Shoba TL, Mulla IS, Vijayamohanan K, Kulkarni SK, Urban J, Vogel W, J. Colloid Interface Sci., 255, 79 (2002)

[18] Feng L, Zhang C, Gao G, Cui D, Nanoscale Res. Lett., 7, 1 (2012)

[19] Murugadoss G, Rajamannan B, Madhusudhanana U, Chalcogenide Lett., 6, 197 (2009)

[20] Lee Y, Choi JR, Lee KJ, Stott NE, Kim D, Nanotechnology, 19, 415604 (2008)

[21] Salavati-Niasari M, Davar F, Mater. Lett., 63, 441 (2009)

[22] Umer A, Naveed S, Ramzan N, Rafique MS, Imran M, Matéria, 19, 197 (2014)

[23] Suresh Y, Annapurna S, Bhikshamaiah G, Singh AK, Int. J. Sci. Eng. Res., 5, 156 (2014)

[24] Raffi M, Mehrwan S, Bhatti TM, Akhter JI, Hameed A, Yawar W, Mahmood UHM, Ann. Microbiol., 60, 75 (2010)

[25] Stoimenov PK, Klinger RL, Marchin GL, Klabunde KG, Langmuir, 18, 6679 (2002)

[26] Mahmoodi S, Elmi A, Hallaj-Nezhadi S, J. Mol. Pharm. Org. Process Res, 6, 140 (2018)

[27] Bayat M, Zargar M, Chudinova E, Astarkhanova T, Pakina E, Molecules, 26, 5402 (2021)

[28] Oussou-Azo AF, Nakama T, Nakamura M, Futagami T, Vestergaard MCM, Nanomaterials, 10, 2 (2020)