Insensitive munitions (IMs) that suit safety requirements have received much attention to prevent an accidental explosion of the munition by external stimuli. For example, 1,3,5-trinitro-1,3,5-triazinane (RDX), a sensitive legacy explosive material with high explosive performance, is usually used together with insensitive explosives such as 2,4,6-triamino-1,3,5-trinitrobenzene (TATB) in IM formulation to fit the safe operational range of sensitivities. In recent decades, the development of new high energy materials (HEMs) with remarkable insensitivities have become a forefront topic of the energetic material field. Herein, we report a novel HEM based on a hexaaza[3.3.3]propellane skeleton, 2,6-dinitro-3,7,10-trioxo- 2,4,6,8,9,11-hexaaza[3.3.3]pro-pellane (5), which was determined to have high explosive performance along with reduced sensitivity to external stimuli. Both the measured explosive performances and the impact sensitivity of 5 were better than those of TATB. We propose 5 as a promising insensitive HEM and a potential candidate for IM.