An investigation is reported on the behavior of amphiphilic cyclodextrins at the air/water interface. Stable surface pressure vs area curves were recorded for many of the materials investigated. The addition of N(CH3)(4)Cl or KCl to the subphase was found to result in a small but reproducible contraction in the isotherms. Preliminary work also showed that Langmuir-Blodgett films of some materials could be built up on solid surfaces, although the resulting layers were of poor quality.