The effect of annealing in UHV on the topographic and electronic structure of the TiO2(110) surface was studied by scanning tunneling microscopy and spectroscopy. Different (1 x n) reconstructions with domain sizes of 5-10 nm were clearly identified in the crystallographic orientation [001]. Two other types of reconstruction with periodicities of 1.69 and 1.82 nm were detected perpendicular to the [1(1) over bar1$] and [<(1)over bar 13>] crystallographic shear directions. The comparison of I/V and dI/dV spectra recorded on (1 x 1) and (1 x 2) terraces and on a disordered phase suggests a definite difference in the oxidation state of the surface Ti atoms of these arrangements.