The interfacial and thermodynamic properties of a nonionic surfactant, poly(oxyethylene(10)) lauryl ether [C12H25(OCH2CH2)(10)OH], in aqueous solution in the presence and the absence of both polyethylene glycol 400 and sucrose have been investigated. Critical micelle concentrations (cmc’s) were determined by surface tension measurements at different additive concentrations and temperatures using a du Nouy tensiometer. From the surface tension data, the surface excess concentration (Gamma), the minimum area per molecule (A(min)), and the surface pressure at the cmc (Pi(cmc)) were evaluated. Thermodynamic parameters of adsorption and micellization were evaluated and discussed. An enthalpy-entropy compensation effect was observed in all solvent systems. Transfer enthalpies of micellization from water to additive solutions which are sensitive to the solvent structure have been computed using the enthalpy of micellization data. Delta Delta H-m degrees,(tr) data were all large and negative, indicating hydrophilic group-additive interaction. The other solution properties of this surfactant like the cloud point, viscosity, foaming, and wetting have been determined in the presence of different concentrations of PEG 400 and sucrose.