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Applied Catalysis A: General, Vol.147, No.2, 407-414, 1996
Hydrogenation of Pyrrole Derivatives .2. Hydrogenations over Supported Noble-Metal Catalysts
The heterogeneous catalytic hydrogenation of 1-methyl-2-pyrroleethanol resulted in 1-methyl-2-pyrrolidineethanol, an important and valuable pharmaceutical intermediate. Various noble metal catalysts on different supports have been screened. The best results were achieved with a carbon supported rhodium catalyst, in non-acidic medium, under mild reaction conditions (6 bar, room temperature). Ruthenium on carbon also showed high activity in this hydrogenation.