Large diameter polymer light conduits are prepared for the first time by UV-curing. The polymer cores of the polymer light conduits are prepared from the copolymerization of various monomer mixtures in FEP tubes by UV curing, where FEP is used as the polymer cladding. The monomer mixtures consist of a multifunctional monomer for adjusting the heat resistance of the polymer cores and a monofunctional monomer for adjusting the flexibility. Experimental results indicate that the properties of the prepared polymer light conduits can be significantly modified by the formulations of the reactant mixtures. The onset thermal decomposition temperatures of the prepared polymer cores are 50 degrees C to 79 degrees C higher than that of the PMMA core. The glass transition temperatures and the refractive indices of the prepared polymer cores decrease from 78 degrees C to -34 degrees C and 1.490 to 1.474, respectively, when the contents of 2-ethyl-hexyl acrylate in the monomer mixtures increase from 0% to 70%. The prepared polymer light conduits conduits have large numerical apertures suitable for wide angle illumination applications.