Transesterification reactions between polyarylate (PAr) and a copolyester (PETG) have been investigated by proton nuclear magnetic resonance (NMR), Fourier-transform infrared spectroscopy (FTIR), and differential scanning calorimetry. Blends of PAr and PETG were prepared by melt mixing and solution-casting with weight fractions of PAr in the blends varying from 0.90 to 0.10. The FETG is a copolyester containing ethylene-1,4-cyclohexylene dimethylene terephthalate. From the thermal analysis of the PAr/PETG melt blends, a single glass transition temperature is observed, which indicates a miscibility between the PAr and PETG. The benzene insoluble fraction of the PAr/PETG (50/50) melt blends and solution-cast blends were characterized using NMR and FTIR. The results of NMR and FTIR support tile conclusion that transesterification reactions between the PAr and PETG occurred under the melt blending conditions applied.