The determination of impact sensitivity of high explosives (HE) is the most commonly used way of evaluating an explosive hazard. Because of the diversity of practical conditions that make an explosion possible, many experimental methods for measuring sensitivity have been developed. Therefore, the prediction of sensitivity to impact of energetic materials is essential. This work discusses a criterion that aids in such screening for all families of energetic substances. This criterion is based on the maximum heat of reaction. The results of our research reveal a satisfactory mutual interfamily relation between both the theoretical criterion of sensitivity (CS) and experimental values.