Separation Science and Technology, Vol.34, No.11, 2251-2258, 1999
Mathematical modeling of a flat-membrane-controlled release device
The closed form solution to a mathematical model of a flat membrane device successfully predicts the release profile of benzoic acid, Physically, the device consists of a given concentration of benzoic acid in octanol (reservoir) bounded by a microporous flat film (Cellgard 2400) with water-filled pores. The prediction shows excellent agreement with the experimentally derived release profile (maximum difference < 10%). Predicted results are obtained from the use of the steady state plus the first term of the transient solution (infinite series) and with the use of the first nonzero eigenvalue.