Vapor-liquid equilibria at 101.3 kPa have been determined for binary systems propyl bromide-i-butanol, propyl bromide-1-chlorobutane and 1-chlorobutane-methyl ethyl ketone. The binary systems propyl bromide-i-butanol and 1-chlorobutane-methyl ethyl ketone exhibit positive deviations from ideal behavior while the binary system propyl bromide-1-chlorobutane behaves ideally. The activity coefficients and boiling point of the solution were correlated with its composition by the Redlich-Kister and Wisniak-Tamir equations.