Liquid- and gas-phase macromixing behavior was studied in gas-liquid high-aspect-ratio reactors stirred with multiple hydrofoil impellers pumping downward. Water, a sodium sulfate solution, and poly(vinylpyrrolidone) solutions of viscosity up to 110 mPa.s were used as the liquid. For characterizing the Liquid phase, mixing time experiments were conducted at various operating conditions, while detecting the response curves at several positions inside the tank. Comparison of the experimental curves with the theoretical ones provided by simple fluid dynamic models showed that the axial dispersion model is quite acceptable. The influence of impeller speed, gas flow rate, and viscosity on the model parameter was studied, and dimensionless relationships are given. The gas behavior was studied by means of the RTD and modeled with the axial dispersion model, which proved good for water and acceptable with coalescence-inhibiting electrolyte solutions. The model parameter dependence on the operating conditions was studied. Comparison between hydrofoil impellers and radial Rushton turbines is also attempted.