A study of the topographical modifications of a PADC polymer substrate under 25 keV-Electron Beam (EB) irradiation is presented. The thickness variations as a function of the electronic fluence are systematically measured and show a fall in thickness. The causes of this phenomenon are discussed. Simulations of the interaction of the 25 keV-EB and the polymer are also carried out with the aim to correlate the deposited energy and the thickness variations.