The affect of the oxygen transfer coefficient on the production of xylitol by bioconversion of xylose present in sugarcane bagasse hemicellulosic hydrolysate using the yeast Candida guilliermondi was investigated. Continuous cultivation was carried out in a 1.25-L, fermenter at 30 degrees C, pH 5.5, 300 rpm, and a dilution rate of 0.03/h, using oxygen transfer coefficients of 10, 20, and 30/h. The results showed that the microbial xylitol production (11 g/L) increased by 108% with the decrease in the oxygen volumetric transfer coefficient from 30 to 20/h. The maximum values of xylitol productivity (0.7 g/[L.h]) and yield (0.58 g/g) were obtained ak(L)a 20/h.