Biotechnology Letters, Vol.23, No.10, 781-786, 2001
Modelling and simulation of the adsorption of the lipase from Geotrichum sp on hydrophobic interaction columns
The Langmuir model fitted well the adsorption isotherms of lipase on the hydrophobic resin. The model parameters, Q(m) and k(d), were affected by NaCl concentration: Q(m) increased from 31 to 80 U g(-1) resin, and k(d) changed from 9.4 to 3 U ml(-1). Column modelling and the simulation data were compared with the experimental data with good agreement. The highest achieved column efficiency was 71%.