In the present work we report on the properties of Cu-Co nanometric multilayers electrodeposited on indium-tin oxide (ITO) glass using a single electrolyte and the pulse potential technique. We investigated the effect of the pulse potentials on the magnetism and magnetoresistance. The ITO glass substrate allows the deposition of the multilayers directly on it and the characterization of their properties without separating them from the substrate. Optimal pulse potential ranges are characterized for both copper and cobalt deposition. The multilayers have a high magnetization and a large magnetoresistance ratio.