Proton ligand dissociation and metal ligand stability constants of 2-acrylamido-2-amino-3-hydroxy pyridine (AAHP) with some transition metal ions in 0.1 M KCl and 50% (v/v) ethanol-water mixture were calculated potentiometrically. In the presence of 2,2'-azobisisobutyronitrile as initiator the proton-polymeric ligand dissociation and metal polymeric ligand stability constants were also evaluated. The influence of temperature on the dissociation of AAHP and the stability of its metal complexes in the monomeric and polymeric forms were critically studied. On the basis of the thermodynamic functions, the dissociation process of AAHP was found nonspontaneous, endothermic, and entropically unfavorable, although the formed metal complexes showed spontaneous, endothermic, and entropically favorable behavior.